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United States Patent and Trademark Office 



UNITED STATES DEPARTMENT OF COMMERCE 
United States Patent and Trademark Office 
Address: COMMISSIONER FOR PATENTS 
P.O. Box 1450 

Alexandria, Virginia 22313-1450 
www.uspto.gov 



NOTICE OF ALLOWANCE AND FEE(S) DUE 



26694 7590 09/09/2003 

VENABLE, BAETJER, HOWARD AND CIVILETTI, LLP 
P.O. BOX 34385 

WASHINGTON, DC 20043-9998 



EXAMINER 



GOLDBERG, JEANINE ANNE 



ART UNIT 



CLASS-SUBCLASS 



1634 

DATE MAILED: 09/09/2003 



435-006000 



APPLICATION NO. 



FILING DATE 



FIRST NAMED INVENTOR 



ATTORNEY DOCKET NO. 



CONFIRMATION NO. 



09/787,292 03/15/2001 Yoshimi Homma 

TITLE OF INVENTION: METHOD FOR THE DIAGNOSIS OF CELL PROLIFERATIVE DISEASE 



31671-169944 



7573 



APPLN. TYPE 



SMALL ENTITY ISSUE FEE PUBLICATION FEE 



TOTAL FEE(S) DUE 



DATE DUE 



nonprovisional NO $1300 $0 $1300 12/09/2003 

THE APPLICATION IDENTIFIED ABOVE HAS BEEN EXAMINED AND IS ALLOWED FOR ISSUANCE AS A PATENT. 
PROSECUTION ON THE MERITS IS CLOSED . THIS NOTICE OF ALLOWANCE IS NOT A GRANT OF PATENT RIGHTS. 
THIS APPLICATION IS SUBJECT TO WITHDRAWAL FROM ISSUE AT THE INITIATIVE OF THE OFFICE OR UPON 
PETITION BY THE APPLICANT. SEE 37 CFR L313 AND MPEP 1308. 

THE ISSUE FEE AND PUBLICATION FEE (IF REQUIRED) MUST BE PAID WITHIN THREE MONTHS FROM THE 
MAILING DATE OF THIS NOTICE OR THIS APPLICATION SHALL BE REGARDED AS ABANDONED, THIS 
STATUTORY PERIOD CANNOT BE EXTENDED . SEE 35 U.S.C. 151. THE ISSUE FEE DUE INDICATED ABOVE 
REFLECTS A CREDIT FOR ANY PREVIOUSLY PAID ISSUE FEE APPLIED IN THIS APPLICATION. THE PTOL-85B (OR 
AN EQUIVALENT) MUST BE RETURNED WITHIN THIS PERIOD EVEN IF NO FEE IS DUE OR THE APPLICATION WILL 
BE REGARDED AS ABANDONED. 



HOW TO REPLY TO THIS NOTICE: 

L Review the SMALL ENTITY status shown above. 

If the SMALL ENTITY is shown as YES, verify your current 
SMALL ENTITY status: 

A. If the status is the same, pay the TOTAL FEE(S) DUE shown 
above. 

B. If the status is changed, pay the PUBLICATION FEE (if 
required) and twice the amount of the ISSUE FEE shown above 
and notify the United States Patent and Trademark Office of the 
change in status, or 



If the SMALL ENTITY is shown as NO: 

A. Pay TOTAL FEE(S) DUE shown above, or 

B. If applicant claimed SMALL ENTITY status before, or is now 
claiming SMALL ENTITY status, check the box below and enclose 
the PUBLICATION FEE and 1/2 the ISSUE FEE shown above. 

□ Applicant claims SMALL ENTITY status. 
See 37 CFR 1.27. 



II. PART B - FEE(S) TRANSMITTAL should be completed and returned to the United States Patent and Trademark Office (USPTO) with 
your ISSUE FEE and PUBLICATION FEE (if required). Even if the fee(s) have already been paid, Part B - Fee(s) Transmittal should be 
completed and returned. If you are charging the fee(s) to your deposit account, section M 4b M of Part B - Fee(s) Transmittal should be 
completed and an extra copy of the form should be submitted. 

III. All communications regarding this application must give the application number. Please direct all communications prior to issuance to 
Mail Stop ISSUE FEE unless advised to the contrary. 

IMPORTANT* REMINDER: Utility patents issuing on applications filed on or after Dec. 12, 1980* may require payment of 
maintenance fees. It is patentee's responsibility to ensure timely payment of maintenance fees when due. 

* " ' Page 1 of 4 # '*" • ' - 



PTOL-85 (Rev. 08/03) Approved for use through 04/30/2004. 



PART B - FEE(S) TRANSMITTAL 



Complete and send this form, together with applicable fee(s), to: Mail Mail Stop ISSUE FEE 

Commissioner for Patents 
Alexandria, Virginia 22313-1450 

or Fax (703)746-4000 

INSTRUCTIONS: This form should be used for transmitting the ISSUE FEE and PUBLICATION FEE (if required). Blocks 1 through 4 should be completed where 
appropriate. All further correspondence including the Patent, advance orders and notification of maintenance fees will be mailed to the current correspondence address as 
indicated unless corrected below or directed otherwise in Block 1, by (a) specifying a new correspondence address; and/or (b) indicating a separate "FEE ADDRESS" for 
maintenance fee notifications. 



CURRENT CORRESPONDENCE ADDRESS (Note: Legibly mark-up with any corrections or use Block 1) 



26694 



7590 



09/09/2003 

VENABLE, BAETJER, HOWARD AND CIVILETTI, LLP 
P.O. BOX 34385 

WASHINGTON, DC 20043-9998 



Note: A certificate of mailing can only be used for domestic mailings of the 
Fee(s) Transmittal. This certificate cannot he used for any other accompanying 

Eapers. Each additional paper, such as an assignment or formal drawing, must 
ave its own certificate of mailing or transmission. 

Certificate of Mailing or Transmission 

I hereby certify that this Fee(s) Transmittal is being deposited with the United 
States Postal Service with sufficient postage for first class mail in an envelope 
addressed to the Mail Stop ISSUE FEE address above, or being facsimile 
transmitted to the USPTO, on the date indicated below. 



(Depositor's name) 



(Signature) 



(Date) 



APPLICATION NO. 



FILING DATE 



FIRST NAMED INVENTOR 



ATTORNEY DOCKET NO. 



CONFIRMATION NO. 



09/787,292 03/15/2001 Yoshimi Homma 

TITLE OF INVENTION: METHOD FOR THE DIAGNOSIS OF CELL PROLIFERATIVE DISEASE 



31671-169944 



7573 



APPLN. TYPE 



SMALL ENTITY 



ISSUE FEE 



PUBLICATION FEE 



TOTAL FEE(S) DUE I DATE DUE 



nonpro visional 



NO 



$1300 



$0 



$1300 



12/09/2003 



EXAMINER 



ART UNIT 



CLASS-SUBCLASS 



GOLDBERG, JEANINE ANNE 



1634 



435-006000 



1. Change of correspondence address or indication of "Fee Address" (37 
CFR 1.J63). 

□ Change of correspondence address (or Change of Correspondence 
Address form PTO/SB/ 122) attached. 

□ "Fee Address" indication (or "Fee Address" Indication form 
PTO/SB/47; Rev 03-02 or more recent) attached. Use of a Customer 
Number is required. 



2. For printing on the patent front page, list (1) the 
names of up to 3 registered patent attorneys or 
agents OR, alternatively, (2) the name of a single 
firm (having as a member a registered attorney or 
agent) and the names of up to 2 registered patent 
attorneys or agents. If no name is listed, no name 
will be printed. 



3. ASSIGNEE NAME AND RESIDENCE DATA TO BE PRINTED ON THE PATENT (print or type) 

PLEASE NOTE: Unless an assignee is identified below, no assignee data will appear on the patent. Inclusion of assignee data is only appropriate when an assignment has 
been previously submitted to the USPTO or is being submitted under separate cover. Completion of this form is NOT a substitute for filing an assignment. 



(A) NAME OF ASSIGNEE 



(B) RESIDENCE: (CITY and STATE OR COUNTRY) 



Please check the appropriate assignee category or categories (will not be printed on the patent); 
4a. The following fee(s) are enclosed: 4b. Payment of Fee(s): 

□ Issue Fee □ A check in the amount of the fee(s) is enclosed. 

□ Publication Fee □ Payment by credit card. Form PTO-203 8 is attached. 



□ individual □ corporation or other private group entity □ government 



□ Advance Order - # of Copies _ 



□ The Director is hereby authorized by charge the required fee(s), or credit any overpayment, to 
Deposit Account Number (enclose an extra copy of this form). 



Director for Patents is requested to apply the Issue Fee and Publication Fee (if any) or to re-apply any previously paid issue fee to the application identified above. 



(Authorized Signature) 



(Date) 



NOTE; The Issue Fee and Publication Fee (if required) will not be accepted from anyone 
other than the applicant; a registered attorney or agent; or the assignee or other party in 
interest as shown by the records of the United States Patent and Trademark Office. 

This collection of information is required by 37 CFR 1.311. The information is required to 
obtain or retain a benefit by the public which is to file (and by the USPTO to process) an 
application. Confidentiality is governed by 35 U.S.C. 122 and 37 CFR 1.14. This collection is 
estimated to take 12 minutes to complete, including gathering, preparing, and submitting the 
completed application form to the USPTO. Time will vary depending upon the individual 
case. Any comments on the* amount of time you require to complete this form and/or 
suggestions for reducing this burden, should be sent to the Chief Information Officer, U.S. 
Patent and Trademark Office,' 4iS. Department of Commerce, Alexandria, Virginia 
22313-1450. DO NOT SEND FEES OR CCfMPLETED FORMS TO THIS ADDRESS. 
SEND TO: Commissioner for Patents, Alexandria, Virginia 223 13-1450. 

Cinder the Paperwork Reduction Act of 1995, no .persons are reauired;4> respond to .a* 
collection of information unless it displays a valid OMB control number* *'*"* ' '* • ; * " 



PTOL-85 (Rev. 08/03) Approved for use through 04/30/2004. 



TRANSMIT THIS FORM WITH FEE(S) 

OMB 065 1-0033 U.S. Patent and Trademark Office; U.S. DEPARTMENT OF COMMERCE 




United States Patent and Trademark Office 



UNITED STATES DEPARTMENT OF COMMERCE 
United States Patent and Trademark Office 
Address: COMMISSIONER FOR PATENTS 
P.O. Box 1450 

Alexandria, Virginia 22313-1450 
www.uspto.gov 



APPLICATION NO. 


FILING DATE 


FIRST NAMED INVENTOR 


ATTORNEY DOCKET NO. 


CONFIRMATION NO. | 


09/787,292 


03/15/2001 


Yoshimi Homma 


31671-169944 


7573 



26694 7590 09/09/2003 

VENABLE, BAETJER, HOWARD AND CIVILETTI, LLP 
P.O. BOX 34385 

WASHINGTON, DC 20043-9998 



EXAMINER 



GOLDBERG, JEANINE ANNE 



ART UNIT 



PAPER NUMBER 



1634 

DATE MAILED: 09/09/2003 



Determination of Patent Term Extension under 35 U.S.C. 154 (b) 

(application filed after June 7, 1995 but prior to May 29, 2000) 

The Patent Term Extension is 0 day(s). Any patent to issue from the above-identified application will include an 
indication of the 0 day extension on the front page. 

If a Continued Prosecution Application (CPA) was filed in the above-identified application, the filing date that 
determines Patent Term Extension is the filing date of the most recent CPA. 

Applicant will be able to obtain more detailed information by accessing the Patent Application Information Retrieval 
(PAIR) system (http://pair.uspto.gov). 

Any questions regarding the Patent Term Extension or Adjustment determination should be directed to the Office of 
Patent Legal Administration at (703) 305-1383. Questions relating to issue and publication fee payments should be 
directed to the Customer Service Center of the Office of Patent Publication at (703) 305-8283. 



•y. ' ■ • Page 3 of 4 

PTOL-85 (Rev. 08/03) Approved for use through 04/30/2004. 




United States Patent and Trademark Office 



UNITED STATES DEPARTMENT OF COMMERCE 
United States Patent and Trademark Office 
Address: COMMISSIONER FOR PATENTS 
P.O. Box 1450 

Alexandria, Virginia 223 J 3-1450 
www.uspto.gov 



APPLICATION NO. 


FILING DATE 


FIRST NAMED INVENTOR 


ATTORNEY DOCKET NO. | 


CONFIRMATION NO. 


09/787,292 


03/15/2001 


Yoshimi Momma 


31671-169944 


7573 



26694 7590 09/09/2003 

VENABLE, BAETJER, HOWARD AND CIVILETTI, LLP 
P.O. BOX 34385 

WASHINGTON, DC 20043-9998 



EXAMINER 



GOLDBERG, JEANINE ANNE 



ART UNIT 



PAPER NUMBER 



1634 

DATE MAILED: 09/09/2003 



Notice of Fee Increase on October 1, 2003 

If a reply to a "Notice of Allowance and Fee(s) Due" is filed in the Office on or after October 1, 2003, then the 
amount due will be higher than that set forth in the "Notice of Allowance and Fee(s) Due" since there will be an 
increase in fees effective on October 1, 2003. See Revision of Patent Fees for Fiscal Year 2004 : Final Rule . 68 Fed. 
Reg. 41532, 41533, 41534 (July 14, 2003). 

The current fee schedule is accessible from (http://www.uspto.gov/main/howtofees.htm). 

If the fee paid is the amount shown on the "Notice of Allowance and Fee(s) Due" but not the correct amount in view 
of the fee increase, a "Notice of Pay Balance of Issue Fee" will be mailed to applicant. In order to avoid processing 
delays associated with mailing of a "Notice of Pay Balance of Issue Fee," if the response to the Notice of Allowance 
is to be filed on or after October 1 , 2003 (or mailed with a certificate of mailing on or after October 1 , 2003), the 
issue fee paid should be the fee that is required at the time the fee is paid. If the issue fee was previously paid, and the 
response to the "Notice of Allowance and Fee(s) Due" includes a request to apply a previously-paid issue fee to the 
issue fee now due, then the difference between the issue fee amount at the time the response is filed and the 
previously-paid issue fee should be paid. See Manual of Patent Examining Procedure . Section 1308.01 (Eighth 
Edition, August 2001). 

Effective October 1, 2003, 37 CFR 1.18 is amended by revising paragraphs (a) through (c) to read as set forth below. 
Section 1.18 Patent post allowance (including issue) fees, 
(a) Issue fee for issuing each original or reissue patent, 



except a design or plant patent: 

By a small entity (Sec. 1.27(a)) $665.00 

By other than a small entity $1,330.00 

(b) Issue fee for issuing a design patent: 

By a small entity (Sec. 1.27(a)) $240.00 

By other than a small entity $480.00 

(c) Issue fee for issuing a plant patent: 

By a small entity (Sec. 1.27(a)) $320.00 

By other than a small entity $640.00 



Questions relating to issue and publication fee payments should be directed to the Customer Service Center of the 
Office of Patent Publication at (703) 305-8283. 

'v. * 

' " Page 4 of 4 * . * , 



PTOL-85 (Rev. 08/03) Approved for use through 04/30/2004.